Turkey to require genetical SMA disease screening before marriage and for newborns

We are initiating a mandatory genetic screening program to screen couples before marriage and their newborns for SMA.

Minister of health fahrettin koca


Turkey announced on Thursday that screening for Spinal Muscular Atrophy (SMA) disease will be required prior to marriage in the country by the end of the month.

“We are implementing the program of SMA screening for all couples before marriage and newborns,” Health Minister Fahrettin Koca told reporters following an SMA Scientific Committee meeting.

“SMA screening is becoming mandatory before marriage,” he added.

“As a result of the screening, couples whose genetic structures carry the risk of giving birth to a baby with SMA can have a child using in vitro fertilization without this risk, if they wish. The cost is covered by our state,” Koca added.

He also noted that SMA’s inclusion in genetic screenings for diseases in newborns in order to catch the illness early, when treatment is effective.

The minister said the new measure would go into effect by the end of the month.

Turkey has been treating SMA Type 1 since 2017, and Type 2 and 3 since 2019, according to Koca.

SMA is a genetic neuromuscular disease characterized by muscle atrophy and weakness, explains the SMA Foundation website. The disease generally manifests early in life and is the leading genetic cause of death in infants and toddlers.

It is the second-most common autosomal recessive disease in humans, after cystic fibrosis. The overall incidence of SMA is about one in 6,000 to one in 10,000 live births, with a carrier frequency as high as one in 40, according to medical news outlet Medscape.

Source: https://www.aa.com.tr/en/health/turkey-to-require-sma-disease-screening-before-marriage/2437082